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- Understanding Hemochromatosis – an In-depth Look at this Iron Overload Disorder
What is Hemochromatosis?
Hemochromatosis is a genetic disorder characterized by abnormal iron accumulation in various organs of the body, especially the liver, heart and pancreas. It occurs due to mutations in genes responsible for regulating iron absorption in the small intestine. The excess iron gets deposited in the organs gradually damaging their structure and function over the years if left untreated.
Causes of Hemochromatosis
The most common type of hemochromatosis is caused due to mutations in the HFE gene present on chromosome 6. The HFE gene produces a protein called HFE which regulates the absorption of iron from food. A faulty HFE gene results in uncontrolled uptake of iron from the intestine leading to iron overload over time. Rarely, hemochromatosis may also be caused due to mutations in other genes involved in iron metabolism like HCP1, TFR2 and FPN1.
Get More Insights On Hemochromatosis
https://www.exoltech.us/blogs/244521/Understanding-Hemochromatosis-An-Often-Overlooked-Genetic-Condition
Understanding Hemochromatosis – an In-depth Look at this Iron Overload Disorder What is Hemochromatosis? Hemochromatosis is a genetic disorder characterized by abnormal iron accumulation in various organs of the body, especially the liver, heart and pancreas. It occurs due to mutations in genes responsible for regulating iron absorption in the small intestine. The excess iron gets deposited in the organs gradually damaging their structure and function over the years if left untreated. Causes of Hemochromatosis The most common type of hemochromatosis is caused due to mutations in the HFE gene present on chromosome 6. The HFE gene produces a protein called HFE which regulates the absorption of iron from food. A faulty HFE gene results in uncontrolled uptake of iron from the intestine leading to iron overload over time. Rarely, hemochromatosis may also be caused due to mutations in other genes involved in iron metabolism like HCP1, TFR2 and FPN1. Get More Insights On Hemochromatosis https://www.exoltech.us/blogs/244521/Understanding-Hemochromatosis-An-Often-Overlooked-Genetic-Condition0 Comments 0 Shares - http://sugar-defenderr-us.com0 Comments 0 Shares
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